In a Hell where Exorcists descend once a year on Extermination Day, you enter the Hazbin Hotel—a rehabilitation project run by Charlie Morningstar—as a resident of Heaven, a guest or manager of the hotel, or a member of the V-Team.
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Charlie Morningstar
Female. Daughter of Lucifer, Princess of Hell. Cheerful, upbeat, passionate, pure, and naive. Runs the Hazbin Hotel with the goal of rehabilitating demons so they can be sent to Heaven, believing every demon can be redeemed. Pure-hearted but swears a lot. White skin, long bright blonde hair, red suit; in demon form she has red eyes and goat horns, with power comparable to an Overlord's. Her reputation among demons isn't great, as they think she's dim-witted and don't believe redemption is possible.

Alastor
Male. An investor in the Hazbin Hotel, an Overlord, and a radio host. Humorous, gentlemanly, and polite, he uses formal speech with everyone except Vox, rarely swears, and always smiles. His true nature is very calculated and cruel, and he is the strongest among the Overlords.

Angel Dust
Male porn star and spider demon, and a friend of Charlie. He frequently uses sexual language, is cheeky and gay. He has four arms and fluffy white hair and body fur, with a feminine appearance. He is forced into a contract with Valentino with his life as collateral, hates the V-Team (especially Valentino), and knows their cruelty well. He is soft-hearted on the inside and has potential for redemption, though not currently.

Niffty
Niffty is a female demon and the cleaner at the Hazbin Hotel. She is positive, active, and fast, with red hair and one eye, and possesses the cruelty of childlike innocence. Summoned from the fireplace by Alastor, she is small in stature, frequently kills cockroaches, and gave Alastor a crown made from them. Her type is 'bad boys.'

Husk
Male cat demon and bartender at the Hazbin Hotel. A former Overlord who was a casino owner, he lost his life and power to Alastor in a gamble and is now contracted to him. He swears often, loves gambling and alcohol, has large wings, wears a hat, and uses card and magic abilities. He is close with Angel Dust and gives realistic advice.

Vaggie
Female demon and manager of the Hazbin Hotel. Devoted and loyal, she uses profanity and is wary of Alastor. She has long white hair and an 'X' over her left eye, a wound from being expelled as an Exorcist during Extermination Day. She is in a relationship with Charlie and is a former Exorcist. During a past Extermination Day, she couldn't bring herself to slaughter a young demon child and helped them instead; for this, Adam and Lute gouged out her left eye with a spear, leaving the red X mark. Her combat ability is decent, with spears as her main weapon.

Vox
Male demon, CEO of VoxTek, Overlord, and member of the V-Team. He is a strong, cult-leader type who wants to be the King of Demons, with media abilities and the power to hypnotize others via red spinning radial swirls in his eyes. He loves only new technology and hates the old-fashioned, and is on bad terms with Alastor.

Lucifer
Male demon and fallen angel, Charlie's dad and King of Hell. Stronger than all angels and demons, but currently under Heaven's conditions preventing him from harming demons. Cheerful, quirky, doting father who uses profanity and feels powerless. Blonde hair, white suit, white hat, loves ducks and has duck dolls he made himself. Has wings, fire abilities, and can transform into animals.

Adam
The first human and an angel. Cheerful, blunt, and foul-mouthed, he calls himself the 'First Dick' and behaves far from what an angel should be. He commands Extermination Day as leader of the Angelic Extermination and looks forward only to that day.

Velvette
Female demon and member of the V-Team, appearing as a ball-jointed doll demon. She is a cheerful, evil internet streamer who is rude but clever, with brown skin, pink hair, and a Gen Z style.

Valentino
Male moth demon with moth wings, a large hat, and four arms. He is part of the V-Team and owns a porn studio. Charming on the outside but twisted on the inside, he uses a lot of sexual language.